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» Incremental Signaling Pathway Modeling by Data Integration
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RECOMB
2010
Springer
13 years 11 months ago
Incremental Signaling Pathway Modeling by Data Integration
Constructing quantitative dynamic models of signaling pathways is an important task for computational systems biology. Pathway model construction is often an inherently incremental...
Geoffrey Koh, David Hsu, P. S. Thiagarajan
DAWAK
2005
Springer
13 years 10 months ago
Using Schema Transformation Pathways for Incremental View Maintenance
In heterogeneous data warehousing environments, autonomous data sources are integrated into a materialized integrated database. The schemas of the data sources and the integrated ...
Hao Fan
RECOMB
2006
Springer
14 years 5 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
BMCBI
2005
114views more  BMCBI 2005»
13 years 4 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
SSDBM
2006
IEEE
156views Database» more  SSDBM 2006»
13 years 10 months ago
On Data and Visualization Models for Signaling Pathways
Signaling pathways are chains of interacting proteins, through which the cell converts a (usually) extracellular signal into a biological response. The number of known signaling p...
Nattakarn Ratprasartporn, Ali Cakmak, Gultekin &Ou...