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» Incremental Signaling Pathway Modeling by Data Integration
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JMLR
2010
105views more  JMLR 2010»
13 years 1 months ago
Evaluation of Signaling Cascades Based on the Weights from Microarray and ChIP-seq Data
In this study, we combined the ChIP-seq and the transcriptome data and integrated these data into signaling cascades. Integration was realized through a framework based on data- a...
Zerrin Isik, Volkan Atalay, Rengül Çet...
RECOMB
2003
Springer
14 years 6 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
CMSB
2003
Springer
13 years 11 months ago
An Overview of Data Models for the Analysis of Biochemical Pathways
Biochemical pathways such as metabolic, regulatory or signal tranduction pathways can be viewed as interconnected processes forming an intricate network of functional and physical...
Yves Deville, David Gilbert, Jacques van Helden, S...
BMCBI
2005
109views more  BMCBI 2005»
13 years 6 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
BMCBI
2005
189views more  BMCBI 2005»
13 years 6 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen