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BMCBI
2008
164views more  BMCBI 2008»
13 years 5 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
CBRMD
2008
167views more  CBRMD 2008»
13 years 5 months ago
Case-based Reasoning for Diagnosis of Stress using Enhanced Cosine and Fuzzy Similarity
Intelligent analysis of heterogeneous data and information sources for efficient decision support presents an interesting yet challenging task in clinical environments. This is par...
Mobyen Uddin Ahmed, Shahina Begum, Peter Funk, Nin...
BMCBI
2006
90views more  BMCBI 2006»
13 years 5 months ago
A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity
Background: Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immun...
Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Mural...
BMCBI
2005
100views more  BMCBI 2005»
13 years 5 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...