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ICDM
2003
IEEE
148views Data Mining» more  ICDM 2003»
13 years 10 months ago
Inference of Protein-Protein Interactions by Unlikely Profile Pair
We note that a set of statistically “unusual” proteinprofile pairs in experimentally determined database of protein-protein interactions can typify protein-protein interaction...
Byung-Hoon Park, George Ostrouchov, Gong-Xin Yu, A...
NIPS
2004
13 years 6 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
CSB
2002
IEEE
230views Bioinformatics» more  CSB 2002»
13 years 10 months ago
Prediction of Protein Function Using Protein-Protein Interaction Data
Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, ...
BMCBI
2005
126views more  BMCBI 2005»
13 years 5 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...
BMCBI
2008
124views more  BMCBI 2008»
13 years 5 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo