Topological relationships like overlap, inside, meet, and disjoint uniquely characterize the relative position between objects in space. For a long time, they have been a focus of...
Many areas of modern biology are concerned with the management, storage, visualization, comparison, and analysis of networks. For instance, networks are used to model signal trans...
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
Background: Comparison of large protein datasets has become a standard task in bioinformatics. Typically researchers wish to know whether one group of proteins is significantly en...
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...