13 search results - page 2 / 3 » Integrative Geometric-Hashing Approaches to Binding Site Mod... |
BMCBI
2006
13 years 5 months ago
2006
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
BMCBI
2010
13 years 6 months ago
2010
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
BMCBI
2007
13 years 5 months ago
2007
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
TCBB
2011
13 years 23 days ago
2011
—Constructing accurate computational models that explain how ions permeate through a biological ion channel is an important problem in biophysics and drug design. Brownian dynami...
RECOMB
2002
Springer
14 years 6 months ago
2002
Springer
We present a probabilistic framework that models the process by which transcriptional binding explains the mRNA expression of different genes. Our joint probabilistic model unifie...