12 search results - page 1 / 3 » Integrative bioinformatics analysis of transcriptional regul... |
BMCBI
2008
13 years 4 months ago
2008
Background: Microarray technology has unveiled transcriptomic differences among tumors of various phenotypes, and, especially, brought great progress in molecular understanding of...
BMCBI
2005
13 years 4 months ago
2005
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
BMCBI
2011
12 years 11 months ago
2011
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
BMCBI
2010
13 years 4 months ago
2010
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
BMCBI
2010
13 years 4 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...