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BMCBI
2005
142views more  BMCBI 2005»
13 years 4 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2005
198views more  BMCBI 2005»
13 years 4 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
NAR
2007
124views more  NAR 2007»
13 years 4 months ago
EVEREST: a collection of evolutionary conserved protein domains
Protein domains are subunits of proteins that recur throughout the protein world. There are many definitions attempting to capture the essence of a protein domain, and several sys...
Elon Portugaly, Nathan Linial, Michal Linial
BMCBI
2005
108views more  BMCBI 2005»
13 years 4 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...