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TIT
2010
88views Education» more  TIT 2010»
12 years 11 months ago
Limits of performance of quantitative polymerase chain reaction systems
Abstract--Estimation of the DNA copy number in a given biological sample is an important problem in genomics. Quantitative polymerase chain reaction (qPCR) systems detect the targe...
Haris Vikalo, Babak Hassibi, Arjang Hassibi
BMCBI
2006
107views more  BMCBI 2006»
13 years 5 months ago
Evaluation of methods for oligonucleotide array data via quantitative real-time PCR
Background: There are currently many different methods for processing and summarizing probelevel data from Affymetrix oligonucleotide arrays. It is of great interest to validate t...
Li-Xuan Qin, Richard P. Beyer, Francesca N. Hudson...
AMC
2006
67views more  AMC 2006»
13 years 5 months ago
A general probabilistic model of the PCR process
Earlier work by Saha et al. rigorously derived a general probabilistic model for the PCR process that includes as a special case the Velikanov-Kapral model where all nucleotide re...
Nilanjan Saha, Layne T. Watson, Karen Kafadar, Ale...
NAR
2008
113views more  NAR 2008»
13 years 4 months ago
miRNAMap 2.0: genomic maps of microRNAs in metazoan genomes
MicroRNAs (miRNAs) are small non-coding RNA molecules that can negatively regulate gene expression and thus control numerous cellular mechanisms. This work develops a resource, mi...
Sheng-Da Hsu, Chia-Huei Chu, Ann-Ping Tsou, Shu-Je...
BMCBI
2010
97views more  BMCBI 2010»
13 years 2 months ago
Preprocessing of gene expression data by optimally robust estimators
Background: The preprocessing of gene expression data obtained from several platforms routinely includes the aggregation of multiple raw signal intensities to one expression value...
Matthias Kohl, Hans-Peter Deigner