Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. It is partially derived f...
John-Marc Chandonia, Nigel S. Walker, Loredana Lo ...
Background: Gene Ontology (GO) terms are often used to assess the results of microarray experiments. The most common way to do this is to perform Fisher's exact tests to find...
Computational and comparative analysis of protein-protein interaction (PPI) networks enable understanding of the modular organization of the cell through identification of functio...
Complex systems exhibit emergent patterns of behavior at different levels of organization. Powerful network analysis methods, developed in physics and social sciences, have been s...
Andre Nash, Christian Bird, Earl T. Barr, Premkuma...