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» Local sequence alignments with monotonic gap penalties
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AINA
2008
IEEE
13 years 12 months ago
Introducing Variable Gap Penalties into Three-Sequence Alignment for Protein Sequences
The common-use gap penalty strategies, constant penalty and affine gap penalty, have been adopted in the traditional three-sequence alignment algorithm which considers the inserti...
Che-Lun Hung, Chun-Yuan Lin, Yeh-Ching Chung, Chua...
JCB
2007
94views more  JCB 2007»
13 years 5 months ago
Locality and Gaps in RNA Comparison
Locality is an important and well-studied notion in comparative analysis of biological sequences. Similarly, taking into account affine gap penalties when calculating biological ...
Rolf Backofen, Shihyen Chen, Danny Hermelin, Gad M...
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 11 months ago
Highly Scalable and Accurate Seeds for Subsequence Alignment
We propose a method for finding seeds for the local alignment of two nucleotide sequences. Our method uses randomized algorithms to find approximate seeds. We present a dynamic ...
Abhijit Pol, Tamer Kahveci
BMCBI
2005
125views more  BMCBI 2005»
13 years 5 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...