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BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
13 years 3 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo
BMCBI
2005
113views more  BMCBI 2005»
13 years 5 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2005
223views more  BMCBI 2005»
13 years 5 months ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
BMCBI
2010
196views more  BMCBI 2010»
13 years 3 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
BMCBI
2008
158views more  BMCBI 2008»
13 years 5 months ago
Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent compo
Background: The analysis of high-throughput gene expression data sets derived from microarray experiments still is a field of extensive investigation. Although new approaches and ...
Dominik Lutter, Peter Ugocsai, Margot Grandl, Evel...