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ICASSP
2007
IEEE
13 years 11 months ago
ML Estimation of DNA Initial Copy Number in Polymerase Chain Reaction (PCR) Processes
Estimation of DNA copy number in a given biological sample is an extremely important problem in genomics. This problem is especially challenging when the number of the DNA strands...
Haris Vikalo, Babak Hassibi, Arjang Hassibi
CSB
2005
IEEE
166views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Automated Validation of Polymerase Chain Reactions Using Amplicon Melting Curves
PCR, the polymerase chain reaction, is a fundamental tool of molecular biology. Quantitative PCR is the goldstandard methodology for determination of DNA copy numbers, quantitatin...
Tobias P. Mann, Richard Humbert, John A. Stamatoya...
TIT
2010
88views Education» more  TIT 2010»
12 years 11 months ago
Limits of performance of quantitative polymerase chain reaction systems
Abstract--Estimation of the DNA copy number in a given biological sample is an important problem in genomics. Quantitative polymerase chain reaction (qPCR) systems detect the targe...
Haris Vikalo, Babak Hassibi, Arjang Hassibi
BMCBI
2008
79views more  BMCBI 2008»
13 years 5 months ago
A high-throughput pipeline for designing microarray-based pathogen diagnostic assays
Background: We present a methodology for high-throughput design of oligonucleotide fingerprints for microarray-based pathogen diagnostic assays. The oligonucleotide fingerprints, ...
Ravi Vijaya Satya, Nela Zavaljevski, Kamal Kumar, ...