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CIBCB
2009
IEEE
13 years 6 months ago
Application of machine learning approaches on quantitative structure activity relationships
Machine Learning techniques are successfully applied to establish quantitative relations between chemical structure and biological activity (QSAR), i.e. classify compounds as activ...
Mariusz Butkiewicz, Ralf Mueller, Danilo Selic, Er...
BMCBI
2007
153views more  BMCBI 2007»
13 years 5 months ago
A new pairwise kernel for biological network inference with support vector machines
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
BMCBI
2007
215views more  BMCBI 2007»
13 years 5 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
ISMB
1993
13 years 6 months ago
Knowledge-Based Generation of Machine-Learning Experiments: Learning with DNA Crystallography Data
Thoughit has been possible in the past to learn to predict DNAhydration patterns from crystallographic data, there is ambiguity in the choice of training data (both in terms of th...
Dawn M. Cohen, Casimir A. Kulikowski, Helen Berman