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BMCBI
2011
12 years 12 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
BMCBI
2008
134views more  BMCBI 2008»
13 years 5 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
TCBB
2008
107views more  TCBB 2008»
13 years 4 months ago
Coclustering of Human Cancer Microarrays Using Minimum Sum-Squared Residue Coclustering
It is a consensus in microarray analysis that identifying potential local patterns, characterized by coherent groups of genes and conditions, may shed light on the discovery of pre...
Hyuk Cho, Inderjit S. Dhillon
BMCBI
2008
103views more  BMCBI 2008»
13 years 5 months ago
Discovering multi-level structures in bio-molecular data through the Bernstein inequality
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Alberto Bertoni, Giorgio Valentini