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BMCBI
2006
233views more  BMCBI 2006»
13 years 6 months ago
AbMiner: A bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic,
Background: Monoclonal antibodies are used extensively throughout the biomedical sciences for detection of antigens, either in vitro or in vivo. We, for example, have used them fo...
Sylvia M. Major, Satoshi Nishizuka, Daisaku Morita...
BMCBI
2011
13 years 13 days ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
ISMB
2008
13 years 8 months ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
13 years 6 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
BMCBI
2008
106views more  BMCBI 2008»
13 years 6 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...