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BMCBI
2010
142views more  BMCBI 2010»
13 years 2 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
BMCBI
2006
143views more  BMCBI 2006»
13 years 5 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2008
156views more  BMCBI 2008»
13 years 5 months ago
The unique probe selector: a comprehensive web service for probe design and oligonucleotide arrays
Background: Nucleic acid hybridization, a fundamental technique in molecular biology, can be modified into very effective and sensitive methods for detecting particular targets mi...
Shu-Hwa Chen, Chen-Zen Lo, Ming-Chi Tsai, Chao A. ...
BMCBI
2007
96views more  BMCBI 2007»
13 years 5 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
GECCO
2006
Springer
154views Optimization» more  GECCO 2006»
13 years 9 months ago
Emergent mating topologies in spatially structured genetic algorithms
The application of network analysis to emergent mating topologies in spatially structured genetic algorithms is presented in this preliminary study as a framework for inferring ev...
Joshua L. Payne, Margaret J. Eppstein