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BMCBI
2004
114views more  BMCBI 2004»
13 years 5 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
APBC
2004
122views Bioinformatics» more  APBC 2004»
13 years 6 months ago
Evolution of Relative Synonymous Codon Usage in Human Immunodeficiency Virus Type 1
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
Peter L. Meintjes, Allen G. Rodrigo
BMCBI
2010
133views more  BMCBI 2010»
13 years 5 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang