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BIOCOMP
2006
13 years 6 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BMCBI
2007
164views more  BMCBI 2007»
13 years 5 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
ESWA
2006
103views more  ESWA 2006»
13 years 5 months ago
Model gene network by semi-fixed Bayesian network
Gene networks describe functional pathways in a given cell or tissue, representing processes such as metabolism, gene expression regulation, and protein or RNA transport. Thus, le...
Tie-Fei Liu, Wing-Kin Sung, Ankush Mittal
BMCBI
2008
201views more  BMCBI 2008»
13 years 5 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
CSB
2002
IEEE
169views Bioinformatics» more  CSB 2002»
13 years 10 months ago
Bayesian Network and Nonparametric Heteroscedastic Regression for Nonlinear Modeling of Genetic Network
We propose a new statistical method for constructing a genetic network from microarray gene expression data by using a Bayesian network. An essential point of Bayesian network con...
Seiya Imoto, SunYong Kim, Takao Goto, Sachiyo Abur...