Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
Abstract. The analysis of large-scale regulatory models using data issued from genome-scale high-throughput experimental techniques is an actual challenge in the systems biology fi...
Carito Guziolowski, Jeremy Gruel, Ovidiu Radulescu...