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» Modeling of cell signaling pathways in macrophages by semant...
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BMCBI
2008
122views more  BMCBI 2008»
13 years 6 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
CMSB
2008
Springer
13 years 7 months ago
A Language for Biochemical Systems
Abstract. CBS is a Calculus of Biochemical Systems intended to allow the modelling of metabolic, signalling and regulatory networks in a natural and modular manner. In this paper w...
Michael Pedersen, Gordon D. Plotkin
HYBRID
2004
Springer
13 years 11 months ago
Modeling Subtilin Production in Bacillus subtilis Using Stochastic Hybrid Systems
The genetic network regulating the biosynthesis of subtilin in Bacillus subtilis is modeled as a stochastic hybrid system. The continuous state of the hybrid system is the concentr...
Jianghai Hu, Wei Chung Wu, Shankar Sastry
BMCBI
2010
118views more  BMCBI 2010»
13 years 6 months ago
Identifying differentially regulated subnetworks from phosphoproteomic data
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
Martin Klammer, Klaus Godl, Andreas Tebbe, Christo...
BMCBI
2010
147views more  BMCBI 2010»
13 years 6 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...