This position paper argues that the operational modelling approaches from the formal methods community can be applied fruitfully within the systems biology domain. The results can ...
Nicola Bonzanni, K. Anton Feenstra, Wan Fokkink, E...
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
Clustering is the process of grouping a set of objects into classes of similar objects. Although definitions of similarity vary from one clustering model to another, in most of th...
Haixun Wang, Wei Wang 0010, Jiong Yang, Philip S. ...
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...