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» Modelling Gene Regulatory Networks
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BMCBI
2007
155views more  BMCBI 2007»
13 years 5 months ago
Current approaches to gene regulatory network modelling
Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network part...
Thomas Schlitt, Alvis Brazma
BIOCOMP
2006
13 years 6 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BMCBI
2007
164views more  BMCBI 2007»
13 years 5 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
COMPLEXITY
2010
173views more  COMPLEXITY 2010»
13 years 9 days ago
Signal-regulated systems and networks
The paper presents the use of signal regulatory networks, a biologically-inspired model based on gene regulatory networks. Signal regulatory networks are a way of understanding a ...
Terence L. van Zyl, Elizabeth Marie Ehlers
BMCBI
2010
164views more  BMCBI 2010»
13 years 5 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...