—We present a model that explains immunological memory as a consequence of the recursive proliferation of reactive and suppressive cells, where the relative proportion of these c...
Background: Computer simulations are of increasing importance in modeling biological phenomena. Their purpose is to predict behavior and guide future experiments. The aim of this ...
Faheem Mitha, Timothy A. Lucas, Feng Feng, Thomas ...
We have constructed a computer model of the cytotoxic T lymphocyte (CTL) response to antigen and the maintenance of immunological memory. Because immune responses often begin with...
Dennis L. Chao, Miles P. Davenport, Stephanie Forr...
The idiotypic network has a long and chequered history in both theoretical immunology and Artificial Immune Systems. In terms of the latter, the drive for engineering applications ...