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» Morphometric Subtyping for a Panel of Breast Cancer Cell Lin...
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ISBI
2009
IEEE
13 years 11 months ago
Morphometric Subtyping for a Panel of Breast Cancer Cell Lines
A panel of cell lines of diverse molecular background offers an improved model system for high-content screening, comparative analysis, and cell systems biology. A computational p...
Ju Han, Hang Chang, Gerald Fontenay, Nicholas J. W...
BMCBI
2010
131views more  BMCBI 2010»
13 years 5 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
EVOW
2006
Springer
13 years 8 months ago
Hierarchical Clustering, Languages and Cancer
In this paper, we introduce a novel objective function for the hierarchical clustering of data from distance matrices, a very relevant task in Bioinformatics. To test the robustnes...
Pritha Mahata, Wagner Costa, Carlos Cotta, Pablo M...
BMCBI
2005
144views more  BMCBI 2005»
13 years 4 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...
RECOMB
2007
Springer
14 years 5 months ago
Framework for Identifying Common Aberrations in DNA Copy Number Data
High-resolution array comparative genomic hybridization (aCGH) provides exon-level mapping of DNA aberrations in cells or tissues. Such aberrations are central to carcinogenesis an...
Amir Ben-Dor, Doron Lipson, Anya Tsalenko, Mark Re...