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» Motifs and Modules in Fractured Functional Yeast Networks
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CIBCB
2007
IEEE
13 years 11 months ago
Motifs and Modules in Fractured Functional Yeast Networks
The integration of diverse data sets into probabilistic functional networks is an active and important area of research in systems biology. In this paper we fracture a previously p...
Jennifer Hallinan, Anil Wipat
BMCBI
2005
169views more  BMCBI 2005»
13 years 5 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2005
95views more  BMCBI 2005»
13 years 5 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
IJBRA
2008
69views more  IJBRA 2008»
13 years 5 months ago
A matrix-based multilevel approach to identify functional protein modules
: Identifying functional modules is believed to reveal most cellular processes. There have been many computational approaches to investigate the underlying biological structures [2...
Suely Oliveira, Sang-Cheol Seok
BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...