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» Motifs in regulatory networks and their structural robustnes...
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BMCBI
2010
183views more  BMCBI 2010»
13 years 2 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2008
142views more  BMCBI 2008»
13 years 5 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2010
152views more  BMCBI 2010»
13 years 5 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
CIBCB
2007
IEEE
13 years 8 months ago
Prediction of Enzyme Catalytic Sites from Sequence Using Neural Networks
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Swati Pande, Amar Raheja, Dennis R. Livesay