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» Multiclass discovery in array data
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BMCBI
2011
13 years 9 days ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
CIBCB
2007
IEEE
13 years 9 months ago
Associative Artificial Neural Network for Discovery of Highly Correlated Gene Groups Based on Gene Ontology and Gene Expression
Abstract-- The advance of high-throughput experimental technologies poses continuous challenges to computational data analysis in functional and comparative genomics studies. Gene ...
Ji He, Xinbin Dai, Xuechun Zhao
BMCBI
2007
123views more  BMCBI 2007»
13 years 5 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
DATAMINE
2008
137views more  DATAMINE 2008»
13 years 5 months ago
Two heads better than one: pattern discovery in time-evolving multi-aspect data
Abstract. Data stream values are often associated with multiple aspects. For example, each value observed at a given time-stamp from environmental sensors may have an associated ty...
Jimeng Sun, Charalampos E. Tsourakakis, Evan Hoke,...
BMCBI
2010
132views more  BMCBI 2010»
13 years 5 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter