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BMCBI
2007
134views more  BMCBI 2007»
13 years 5 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
SIGOPS
2008
119views more  SIGOPS 2008»
13 years 5 months ago
Project Kittyhawk: building a global-scale computer: Blue Gene/P as a generic computing platform
This paper describes Project Kittyhawk, an undertaking at IBM Research to explore the construction of a nextgeneration platform capable of hosting many simultaneous web-scale work...
Jonathan Appavoo, Volkmar Uhlig, Amos Waterland
BIOCOMP
2006
13 years 6 months ago
The Generalized Topological Overlap Matrix for Detecting Modules in Gene Networks
Systems biologic studies of gene and protein interaction networks have found that these networks are comprised of `modules' (groups of tightly interconnected nodes). Module i...
Andy M. Yip, Steve Horvath
ALMOB
2006
135views more  ALMOB 2006»
13 years 5 months ago
P-value based visualization of codon usage data
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
CSDA
2008
128views more  CSDA 2008»
13 years 5 months ago
Assessing agreement of clustering methods with gene expression microarray data
In the rapidly evolving field of genomics, many clustering and classification methods have been developed and employed to explore patterns in gene expression data. Biologists face...
Xueli Liu, Sheng-Chien Lee, George Casella, Gary F...