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BMCBI
2005
142views more  BMCBI 2005»
13 years 5 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2007
135views more  BMCBI 2007»
13 years 5 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer
BIOCOMP
2006
13 years 6 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh
NAR
2006
128views more  NAR 2006»
13 years 5 months ago
Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee
Expresso is a multiple sequence alignment server that aligns sequences using structural information. The user only needs to provide sequences. The server runs BLAST to identify cl...
Fabrice Armougom, Sébastien Moretti, Olivie...
GECCO
2008
Springer
165views Optimization» more  GECCO 2008»
13 years 6 months ago
Multiple sequence alignment using a GLOCSA guided genetic algorithm
This paper introduces GLOCSA as a new scoring function to rate multiple sequence alignments. It is intended to be simple, considering the whole alignment at once and reflecting t...
Edgar David Arenas-Díaz, Helga Ochoterena-B...