53 search results - page 10 / 11 » Multiple sequence alignment accuracy and evolutionary distan... |
BMCBI
2010
13 years 5 months ago
2010
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
BMCBI
2008
13 years 5 months ago
2008
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
BMCBI
2006
13 years 5 months ago
2006
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
BMCBI
2008
13 years 5 months ago
2008
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
BMCBI
2006
13 years 5 months ago
2006
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...