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» Mutual Information Content of Homologous DNA Sequences
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BIOCOMP
2008
13 years 7 months ago
Analysis of Protein-Ligand Interactions Using Localized Stereochemical Features
Computational analyses of protein structure-function relationships have traditionally been based on sequence homology, fold family analysis and 3D motifs/templates. Previous struct...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
BMCBI
2011
13 years 24 days ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch
BMCBI
2011
12 years 9 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
SIGMOD
2007
ACM
169views Database» more  SIGMOD 2007»
14 years 6 months ago
Genome-scale disk-based suffix tree indexing
With the exponential growth of biological sequence databases, it has become critical to develop effective techniques for storing, querying, and analyzing these massive data. Suffi...
Benjarath Phoophakdee, Mohammed J. Zaki
BMCBI
2006
118views more  BMCBI 2006»
13 years 5 months ago
Automatic generation of gene finders for eukaryotic species
Background: The number of sequenced eukaryotic genomes is rapidly increasing. This means that over time it will be hard to keep supplying customised gene finders for each genome. ...
Kasper Munch, Anders Krogh