314 search results - page 1 / 63 » On Suboptimal Alignments of Biological Sequences |
CPM
1993
Springer
13 years 9 months ago
1993
Springer
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re
ect the correct biolog...
BIBE
2005
IEEE
13 years 10 months ago
2005
IEEE
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
WABI
2004
Springer
13 years 10 months ago
2004
Springer
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
BIOCOMP
2007
13 years 6 months ago
2007
Low-Complexity Regions (LCRs) of biological sequences are the main source of false positives in similarity searches for biological sequence databases. We consider the problem of ï...
AINA
2006
IEEE
13 years 11 months ago
2006
IEEE
Multiple sequence alignment is an important and difficult problem in molecular biology and bioinformatics. In this paper, we propose a partitioning approach that significantly impr...