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» On consensus biomarker selection
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AAAI
2012
11 years 7 months ago
A Dynamic Rationalization of Distance Rationalizability
Distance rationalizability is an intuitive paradigm for developing and studying voting rules: given a notion of consensus and a distance function on preference profiles, a ration...
Craig Boutilier, Ariel D. Procaccia
BMCBI
2010
146views more  BMCBI 2010»
13 years 4 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
BMCBI
2008
135views more  BMCBI 2008»
13 years 4 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
BIOCOMP
2007
13 years 6 months ago
Biomarker Discovery Across Annotated and Unannotated Microarray Datasets Using Semi-Supervised Learning
The growing body of DNA microarray data has the potential to advance our understanding of the molecular basis of disease. However annotating microarray datasets with clinically us...
Cole Harris, Noushin Ghaffari
CMPB
2011
69views more  CMPB 2011»
12 years 11 months ago
Modelling acute renal failure using blood and breath biomarkers in rats
: This paper compares three methods for estimating renal function, tested in rats. Acute Renal Failure (ARF) was induced via a 60-minute bilateral renal artery clamp in 8 Sprague-D...
Katherine T. Moorhead, Jonathan V. Hill, J. Geoffr...