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RECOMB
2003
Springer
14 years 5 months ago
On de novo interpretation of tandem mass spectra for peptide identification
The correct interpretation of tandem mass spectra is a difficult problem, even when it is limited to scoring peptides against a database. De novo sequencing is considerably harder...
Vineet Bafna, Nathan Edwards
BMCBI
2010
152views more  BMCBI 2010»
13 years 5 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
ECCB
2008
IEEE
13 years 6 months ago
Towards de novo identification of metabolites by analyzing tandem mass spectra
Abstract. Mass spectrometry is among the most widely used technologies in proteomics and metabolomics. For metabolites, de novo interpretation of spectra is even more important tha...
Sebastian Böcker, Florian Rasche
IMSCCS
2006
IEEE
13 years 11 months ago
Quality Assessment of Peptide Tandem Mass Spectra
Background: Tandem mass spectrometry has emerged as a cornerstone of high throughput proteomic studies owing in part to various high throughput search engines which are used to in...
Fang-Xiang Wu, Pierre Gagné, Arnaud Droit, ...
DAGM
2006
Springer
13 years 8 months ago
Probabilistic De Novo Peptide Sequencing with Doubly Charged Ions
Sequencing of peptides by tandem mass spectrometry has matured to the key technology for proteomics. Noise in the measurement process strongly favors statistical models like NovoHM...
Hansruedi Peter, Bernd Fischer, Joachim M. Buhmann