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BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
BIBM
2007
IEEE
162views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
Multiple Interacting Subcellular Structure Tracking by Sequential Monte Carlo Method
With the wide application of green fluorescent protein (GFP) in the study of live cells, there is a surging need for the computer-aided analysis on the huge amount of image seque...
Quan Wen, Jean Gao, Kate Luby-Phelps
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
BMCBI
2004
115views more  BMCBI 2004»
13 years 5 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
BMCBI
2008
147views more  BMCBI 2008»
13 years 5 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...