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» On the Complexity of Finding Emerging Patterns
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BMCBI
2008
144views more  BMCBI 2008»
13 years 5 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
BMCBI
2008
195views more  BMCBI 2008»
13 years 5 months ago
Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
Fredrik Pettersson, Andrew P. Morris, Michael R. B...
BMCBI
2010
124views more  BMCBI 2010»
13 years 5 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2006
114views more  BMCBI 2006»
13 years 5 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
TCAD
2008
128views more  TCAD 2008»
13 years 5 months ago
Obstacle-Avoiding Rectilinear Steiner Tree Construction Based on Spanning Graphs
Given a set of pins and a set of obstacles on a plane, an obstacle-avoiding rectilinear Steiner minimal tree (OARSMT) connects these pins, possibly through some additional points (...
Chung-Wei Lin, Szu-Yu Chen, Chi-Feng Li, Yao-Wen C...