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» Ontology Design Patterns for bio-ontologies: a case study on...
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BMCBI
2006
138views more  BMCBI 2006»
13 years 5 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2005
116views more  BMCBI 2005»
13 years 5 months ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
BMCBI
2007
140views more  BMCBI 2007»
13 years 5 months ago
From genes to functional classes in the study of biological systems
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Fátima Al-Shahrour, Leonardo Arbiza, Hern&a...
BMCBI
2007
153views more  BMCBI 2007»
13 years 5 months ago
MPHASYS: a mouse phenotype analysis system
Background: Systematic, high-throughput studies of mouse phenotypes have been hampered by the inability to analyze individual animal data from a multitude of sources in an integra...
R. Brent Calder, Rudolf B. Beems, Harry van Steeg,...
EDBT
2012
ACM
228views Database» more  EDBT 2012»
11 years 7 months ago
Towards scalable data integration under constraints
In this paper we consider the problem of answering queries using views, with or without ontological constraints, which is important for data integration, query optimization, and d...
George Konstantinidis, José Luis Ambite