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» Optimal control for combination therapy in cancer
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CDC
2008
IEEE
13 years 11 months ago
Optimal control for combination therapy in cancer
Abstract— A mathematical model for the scheduling of angiogenic inhibitors in combination with a killing agent is considered as an optimal control problem. Initial results on the...
Urszula Ledzewicz, Heinz Schättler, Alberto d...
CDC
2009
IEEE
119views Control Systems» more  CDC 2009»
13 years 9 months ago
Optimal controlled trajectories for a mathematical model of anti-angiogenic therapy in cancer
Abstract— Anti-angiogenic therapy is a novel treatment approach in cancer therapy that aims at preventing a tumor from developing a network of blood vessels and capillaries that ...
Urszula Ledzewicz, Heinz Schättler
IOR
2006
126views more  IOR 2006»
13 years 4 months ago
A New Linear Programming Approach to Radiation Therapy Treatment Planning Problems
We consider the problem of radiation therapy treatment planning for cancer patients. During radiation therapy, beams of radiation pass through a patient, killing both cancerous an...
H. Edwin Romeijn, Ravindra K. Ahuja, James F. Demp...
INFORMS
2010
145views more  INFORMS 2010»
13 years 3 months ago
An Automated Intensity-Modulated Radiation Therapy Planning System
We design and implement an intensity-modulated radiation therapy (IMRT) plan generation technology that effectively and efficiently optimizes beam geometry as well as beam intens...
Shabbir Ahmed, Ozan Gozbasi, Martin W. P. Savelsbe...
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li