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» Optimal spliced alignments of short sequence reads
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BIBE
2007
IEEE
128views Bioinformatics» more  BIBE 2007»
14 years 3 days ago
QOMA2: Optimizing the alignment of many sequences
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Xu Zhang, Tamer Kahveci
BMCBI
2005
142views more  BMCBI 2005»
13 years 5 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2010
153views more  BMCBI 2010»
13 years 5 months ago
Pash 3.0: A versatile software package for read mapping and integrative analysis of genomic and epigenomic variation using massi
Background: Massively parallel sequencing readouts of epigenomic assays are enabling integrative genome-wide analyses of genomic and epigenomic variation. Pash 3.0 performs sequen...
Cristian Coarfa, Fuli Yu, Christopher A. Miller, Z...
SIGMOD
2011
ACM
150views Database» more  SIGMOD 2011»
12 years 8 months ago
WHAM: a high-throughput sequence alignment method
Over the last decade the cost of producing genomic sequences has dropped dramatically due to the current so called “next-gen” sequencing methods. However, these next-gen seque...
Yinan Li, Allison Terrell, Jignesh M. Patel
LATA
2010
Springer
13 years 11 months ago
A Randomized Numerical Aligner (rNA)
With the advent of new sequencing technologies able to produce an enormous quantity of short genomic sequences, new tools able to search for them inside a references sequence genom...
Alberto Policriti, Alexandru I. Tomescu, Francesco...