36 search results - page 7 / 8 » Optimal spliced alignments of short sequence reads |
BMCBI
2006
13 years 5 months ago
2006
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
RECOMB
2004
Springer
14 years 6 months ago
2004
Springer
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
BMCBI
2010
13 years 5 months ago
2010
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
NAR
2010
13 years 16 days ago
2010
Chromosome translocations and gene fusions are frequent events in the human genome and have been found to cause diverse types of tumor. ChimerDB is a knowledgebase of fusion genes...
BMCBI
2006
13 years 5 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...