20 search results - page 1 / 4 » Optimization based automated curation of metabolic reconstru... |
BMCBI
2007
13 years 4 months ago
2007
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...
BIRD
2008
Springer
13 years 6 months ago
2008
Springer
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
BMCBI
2007
13 years 4 months ago
2007
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
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BMCBI
2010
13 years 4 months ago
2010
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
CMSB
2007
Springer
13 years 11 months ago
2007
Springer
Abstract. One of the main challenges in systems biology is the establishment of the metabolome: a catalogue of the metabolites and biochemical reactions present in a specific orga...