Sciweavers

14 search results - page 1 / 3
» Optimization of Bacterial Strains with Variable-Sized Evolut...
Sort
View
CIBCB
2007
IEEE
13 years 6 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...
EPIA
2007
Springer
13 years 10 months ago
Evaluating Simulated Annealing Algorithms in the Optimization of Bacterial Strains
Abstract. In this work, a Simulated Annealing (SA) algorithm is proposed for a Metabolic Engineering task: the optimization of the set of gene deletions to apply to a microbial str...
Miguel Rocha, Rui Mendes, Paulo Maia, José ...
BMCBI
2008
150views more  BMCBI 2008»
13 years 4 months ago
MOSAIC: an online database dedicated to the comparative genomics of bacterial strains at the intra-species level
Background: The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been...
Hélène Chiapello, Annie Gendrault, C...
GECCO
2007
Springer
159views Optimization» more  GECCO 2007»
13 years 8 months ago
Discrimination of metabolic flux profiles using a hybrid evolutionary algorithm
Studying metabolic fluxes is a crucial aspect of understanding biological phenotypes. However, it is often not possible to measure these fluxes directly. As an alternative, fluxom...
Stefan Bleuler, Eckart Zitzler
BMCBI
2008
179views more  BMCBI 2008»
13 years 4 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...