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CSB
2005
IEEE
116views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Oscillatory dynamics in the mitogen-activated protein kinase cascade
We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
K.-H. Chiam, Vipul Bhargava, Gunaretnam Rajagopal
SIGMETRICS
2008
ACM
130views Hardware» more  SIGMETRICS 2008»
13 years 4 months ago
Using probabilistic model checking in systems biology
Probabilistic model checking is a formal verification framework for systems which exhibit stochastic behaviour. It has been successfully applied to a wide range of domains, includ...
Marta Z. Kwiatkowska, Gethin Norman, David Parker
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Information transfer in signaling pathways: A study using coupled simulated and experimental data
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...
Jürgen Pahle, Anne K. Green, C. Jane Dixon, U...