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» Overlapping genes in vertebrate genomes
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NAR
2011
158views Computer Vision» more  NAR 2011»
12 years 8 months ago
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research a...
Oliver S. Burren, Ellen C. Adlem, Premanand Achuth...
BMCBI
2005
108views more  BMCBI 2005»
13 years 5 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
BMCBI
2007
131views more  BMCBI 2007»
13 years 5 months ago
An improved method for identifying functionally linked proteins using phylogenetic profiles
Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
BMCBI
2011
13 years 24 days ago
Tiling array data analysis: a multiscale approach using wavelets
Background: Tiling array data is hard to interpret due to noise. The wavelet transformation is a widely used technique in signal processing for elucidating the true signal from no...
Alexander Karpikov, Joel S. Rozowsky, Mark Gerstei...
WABI
2007
Springer
139views Bioinformatics» more  WABI 2007»
13 years 12 months ago
Computability of Models for Sequence Assembly
Graph-theoretic models have come to the forefront as some of the most powerful and practical methods for sequence assembly. Simultaneously, the computational hardness of the underl...
Paul Medvedev, Konstantinos Georgiou, Gene Myers, ...