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ISMB
1998
13 years 6 months ago
BioSim: A New Qualitative Simulation Environment for Molecular Biology
Traditionally, biochemical systems are modelled usingkinetics anddifferential equationsin a quantitative simulator. However,for manybiological processes detailed quantitative info...
Karsten R. Heidtke, Steffen Schulze-Kremer
BIOINFORMATICS
2011
12 years 11 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
BMCBI
2010
129views more  BMCBI 2010»
13 years 4 months ago
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks
Background: Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological fu...
Lina Chen, Hong Wang, Liangcai Zhang, Wan Li, Qian...
JMLR
2010
145views more  JMLR 2010»
12 years 11 months ago
Event based text mining for integrated network construction
The scientific literature is a rich and challenging data source for research in systems biology, providing numerous interactions between biological entities. Text mining technique...
Yvan Saeys, Sofie Van Landeghem, Yves Van de Peer
BMCBI
2005
292views more  BMCBI 2005»
13 years 4 months ago
Atlas - a data warehouse for integrative bioinformatics
Background: We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional a...
Sohrab P. Shah, Yong Huang, Tao Xu, Macaire M. S. ...