30 search results - page 2 / 6 » Pathway-based analysis using reduced gene subsets in genome-... |
BMCBI
2011
12 years 11 months ago
2011
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
EVOW
2005
Springer
13 years 10 months ago
2005
Springer
Abstract. Clustering still represents the most commonly used technique to analyze gene expression data—be it classical clustering approaches that aim at finding biologically rel...
JCB
2008
13 years 4 months ago
2008
Large-scale whole genome association studies are increasingly common, due in large part to recent advances in genotyping technology. With this change in paradigm for genetic studi...
BMCBI
2010
13 years 2 months ago
2010
Background: Most genomic data have ultra-high dimensions with more than 10,000 genes (probes). Regularization methods with L1 and Lp penalty have been extensively studied in survi...
BMCBI
2005
13 years 4 months ago
2005
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...