66 search results - page 2 / 14 » Pedigree Generation for Analysis of Genetic Linkage and Asso... |
BMCBI
2006
13 years 5 months ago
2006
Background: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are exc...
BMCBI
2006
13 years 5 months ago
2006
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
IPPS
2002
IEEE
13 years 10 months ago
2002
IEEE
We present a parallel algorithm for performing multipoint linkage analysis of genetic marker data on large family pedigrees. The algorithm effectively distributes both the computa...
BMCBI
2010
13 years 3 months ago
2010
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
RECOMB
2003
Springer
14 years 6 months ago
2003
Springer
Genetic linkage analysis is a challenging application which requires Bayesian networks consisting of thousands of vertices. Consequently, computing the likelihood of data, which i...