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BIOINFORMATICS
2006
66views more  BIOINFORMATICS 2006»
13 years 5 months ago
Peptide length-based prediction of peptide-MHC class II binding
Stewart T. Chang, Debashis Ghosh, Denise E. Kirsch...
BMCBI
2008
115views more  BMCBI 2008»
13 years 5 months ago
Improving peptide-MHC class I binding prediction for unbalanced datasets
Background: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such bin...
Ana Paula Sales, Georgia D. Tomaras, Thomas B. Kep...
BMCBI
2010
109views more  BMCBI 2010»
13 years 5 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2010
110views more  BMCBI 2010»
13 years 5 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
RECOMB
2005
Springer
14 years 5 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz