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BMCBI
2010
96views more  BMCBI 2010»
13 years 5 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
GECCO
2006
Springer
135views Optimization» more  GECCO 2006»
13 years 9 months ago
Single and multi-objective genetic operators in object-oriented conceptual software design
This poster paper investigates the potential of single and multiobjective genetic operators with an object-oriented conceptual design space. Using cohesion as an objective fitness...
Christopher L. Simons, Ian C. Parmee
FPL
2004
Springer
109views Hardware» more  FPL 2004»
13 years 10 months ago
Hardware Accelerated Novel Protein Identification
The proteins in living organisms perform almost every significant function that governs life. A protein's functionality depends upon its physical structure, which depends on i...
Anish Alex, Jonathan Rose, Ruth Isserlin-Weinberge...
BMCBI
2010
190views more  BMCBI 2010»
13 years 5 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...
BMCBI
2005
157views more  BMCBI 2005»
13 years 5 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...